Wherever testing can show the way forward,
Good Start Genetics offers an option
Good Start Genetics offers a portfolio of genetic testing products that prepares patients for the
next step on their reproductive journey. Whatever the need, versatile options from Good Start
Genetics empower you and your patients with the information you need to make important reproductive
GeneVu: Putting information to work
To be truly valuable to you and your patients, carrier screening must be a means to guiding
more informed decisions. That’s why there’s GeneVu. GeneVu carrier screening tests for severe,
prevalent, and costly genetic disorders, using the technology that provides the most insight.
With the expert support of Good Start Genetics’ lab directors and team of board-certified
genetic counselors, GeneVu helps you and your patients get more out of carrier screening.
Unique, accurate, and comprehensive
Advancing the technology of carrier screening is in our DNA at Good Start Genetics. We developed
the first extensively validated next-generation DNA sequencing (NGS) method for carrier
screening.1,2 It's a unique approach that employs multiple patented process steps.
And it provides the accuracy and completeness that make carrier screening truly useful. GeneVu
generates higher detection rates than traditional genotyping,1,3 which means fewer
missed carriers, lower residual risks, and greater confidence in a negative result.
Tests that matter, information that means more
With GeneVu, advanced technology is applied to guideline-recommended tests for a validated
combination of accuracy and relevance. Our ScreenSelect tool makes it easy to select the tests
most relevant to the patient’s family history and ethnicity. And when GeneVu results are returned,
the patient results report focuses on relevant mutations of known significance.
With compassion and expertise, Good Start Genetics counselors help couples understand their GeneVu
results so they can make informed decisions. Personalized prescreen counseling helps patients get
the tests that are right for them; follow-up counseling ensures that they understand their results
and feel empowered to make decisions. Our job isn’t over until your patient understands the results
and feels ready for what’s next.
Support that keeps you moving
Good Start Genetics works closely with reproductive health centers to integrate GeneVu into your
workflow so that you receive seamless, intuitive delivery of our carrier screening. We create a
simple, understandable, self-guided experience for the patient while making carrier screening
easy for the provider. It’s a better patient experience. And a better experience for your clinic.
EmbryVu: PGS for more of your patients
Preimplantation genetic screening (PGS) is fast becoming a critical step in optimizing IVF outcomes.
It can improve pregnancy rates, lower the incidence of miscarriage, promote success in patients
undergoing single-embryo transfer, and increase the likelihood of having a healthy baby.4-6
But costly technologies have kept many IVF couples from receiving the benefits of PGS. Until now.
Now there’s EmbryVu, which puts high-quality PGS within reach of more IVF couples.
IVF patients who may benefit from PGS include:
- Patients of any age with a history of unsuccessful IVF cycles (repeated implantation failure)*
- Women of advanced maternal age – 35 and older
- Patients with 1 or more miscarriages*
- Patients who have had previous pregnancies with chromosomal abnormalities
- Patients with male factor infertility*
- Patients interested in learning the sex of their embryo
EmbryVu is designed to assess whole chromosome gain or loss. Alternate testing may be
necessary if a partial loss or gain of chromosomal material is suspected.
Quality and affordability
EmbryVu advances the technology of PGS to help more couples undergoing IVF achieve a successful
pregnancy. Only EmbryVu:
Leverages the power of Good Start Genetics’ next-generation sequencing (NGS) technology –
validated for analysis of whole chromosome copy number detection in biopsies from blastocysts
intended for frozen transfer
Employs FAST-SeqS, an innovative NGS-based technology developed at Johns Hopkins
Uses a targeted amplification process that reduces cost and streamlines the laboratory
workflow while maintaining accuracy and quality
Provides automated sample tracking and processing through proprietary labeling and robotics
Easier for everyone
Good Start Genetics supports patients and the IVF center throughout the PGS process. Our
laboratory directors are on hand to answer questions and provide support wherever it’s needed.
And our genetic counselors are available to help patients understand PGS and decide whether
it’s right for them. Results are promptly reported with clarity so clinicians can quickly
determine the next steps for embryo transfer.
Your testing needs — covered
With GeneVu and EmbryVu, Good Start Genetics can provide you with testing tools for important
steps along the reproductive journey, with more options coming in the future. Ask your Good Start
Genetics representative for more information or contact us.
Hallam S, Nelson H, Greger V, et al. Validation for clinical use of, and initial clinical experience
with, a novel approach to population-based carrier screening using high-throughput, next-generation
DNA sequencing. J Mol Diagn. 2014;16(2):180-189.
Umbarger MA, Kennedy CJ, Saunders P, et al. Next-generation carrier screening. Genet Med.
Perreault-Micale C, Davie J, Breton B, Hallam S, Greger V. A rigorous approach for selection of optimal
variant sets for carrier screening with demonstration of clinical utility. Mol Genet Genom Med.
Yang Z, Liu J, Collins GS, et al. Selection of single blastocysts for fresh transfer via standard
morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized
pilot study. Mol Cytogenet. 2012;5(1):24.
Keltz MD, Vega M, Sirota I, et al. Preimplantation genetic screening (PGS) with 139 Comparative genomic
hybridization (CGH) following day 3 single cell blastomere biopsy markedly improves IVF outcomes while
lowering multiple pregnancies and miscarriages. J Assist Reprod Genet. 2013;30(10):1333-1339.
Forman EJ, Hong KH, Ferry KM, et al. In vitro fertilization with single euploid blastocyst transfer: a
randomized controlled trial. Fertil Steril. 2013;100(1):100-107
Kinde I, Papadopoulos N, Kinzler KW, Vogelstein B. FAST-SeqS: a simple and efficient method for the
detection of aneuploidy by massively parallel sequencing. PLoS One. 2012;7(7):e41162.